Muscling up the heart: a preadolescent cardiomyocyte proliferation contributes to heart growth.
نویسندگان
چکیده
منابع مشابه
No Evidence for Cardiomyocyte Number Expansion in Preadolescent Mice
The magnitude of cardiomyocyte generation in the adult heart has been heavily debated. A recent report suggests that during mouse preadolescence, cardiomyocyte proliferation leads to a 40% increase in the number of cardiomyocytes. Such an expansion would change our understanding of heart growth and have far-reaching implications for cardiac regeneration. Here, using design-based stereology, we ...
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The human heart is believed to grow by enlargement but not proliferation of cardiomyocytes (heart muscle cells) during postnatal development. However, recent studies have shown that cardiomyocyte proliferation is a mechanism of cardiac growth and regeneration in animals. Combined with evidence for cardiomyocyte turnover in adult humans, this suggests that cardiomyocyte proliferation may play an...
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ورودعنوان ژورنال:
- Circulation research
دوره 115 8 شماره
صفحات -
تاریخ انتشار 2014